|
KMID : 0616120080390030237
|
|
Korean Journal of Pharmacognosy
2008 Volume.39 No. 3 p.237 ~ p.240
|
|
|
Antitumor Activity of Health Food-C22
|
|
Jin Wen-Yi
Yoo Jae-Kuk
Park Byeong-Wook
Chen Quan-Cheng
Bae Ki-Hwan
|
|
|
Abstract
|
|
|
|
C-22 is one of health food made in Han Kook Shin Yak. For studying its antitumor activity, the 50% ethanol extract from C-22 was tested on BDF1 mice bearing LLC tumor cell by Teruhiro’s method. The samples were intraperitoneally injected to mice once a day with a daily dose of 50, 100, and 200 mg/kg for 14 consecutive days. Taxol was used as positive control with a dose of 50 mg/kg. As a result, the C-22’s extracts dose dependently inhibited the tumor volume with the IRTV values of 28.7, 46.7, 58.9% and the IRTW values of 28.1, 46.0, 57.8% in 50, 100, and 200 mg/kg, respectively, while the Taxol showed antitumor activity with IRTV and IRTW values of 68.5 and 67.3% in 50 mg/kg. No loss of body weight was observed at any samples. This data suggested that the C-22’s antitumor activity was enough to use as a cancer chemopreventive agent, and it will be used for preventing cancer as health food.
|
|
|
KEYWORD
|
|
|
C-22, health food, HanKook ShinYak, LLC tumor cell, antitumor
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|